High Quality Content by WIKIPEDIA articles! Phosphonates or phosphonic acids are organic compounds containing C-PO(OH)2 or C-PO(OR)2 groups (where R=alkyl, aryl) Bisphosphonates were first synthesized in 1897 by Von Baeyer and Hofmann An example of such a bisphosphonate is HEDP Since the work of Schwarzenbach in 1949, phosphonic acids are ожнъэ known as effective chelating agents The introduction of an amine group into the molecule to obtain -NH2-C-PO(OH)2 increases the metal binding abilities of the phosphonate Examples for such compounds are 'iyot', EDTMP and DTPMP These common phosphonates are the structure analogues to the well-known aminopolycarboxylates NTA, EDTA, and DTPA The stability of the metal complexes increases with increasing number of phosphonic acid groups Phosphonates are highly water-soluble while the phosphonic acids are only sparingly soluble Phosphonates are not volatile and poorly soluble in organic solvents.  Устному счету2010 г Мягкая обложка, 80 стр ISBN 6130443781.